Feeds:
Posts
Comments

Post_Cycle_TherapyThere are some chemicals available that can be incorporated into a post cycle therapy depending upon the needs of the athlete. A SERM (Selective Estrogen Receptor Modulator) like Clomid (Clomiphene Citrate) or Nolvadex (Tamoxifen Citrate) should ideally always be incorporated into the schedule. Before these are administered, the testosterone levels need to be brought to normal.

The leydig cells in the testes need to be stimulated by the Luteinizing Hormone (LH) to produce testosterone on their own. LH needs to be produced by the pituitary gland and the pituitary, in turn, needs to be stimulated by the hypothalamus to do that. But the hypothalamus will not stimulate the pituitary as long as there are excess levels of estrogen in the blood stream. This is why another hormone called the HCG needs to be introduced into the body.

The HCG, or the Human Chorionic Gonadotropin hormone, is produced in the human body by the fertilized egg in a pregnant woman. However, this hormone acts like the LH and can stimulate the leydig cells to generate testosterone. The HCG should, however, be used only as minimally as possible – just enough to bring the testes to start producing testosterone on their own again. The HCG can also be used by athletes who suffer testicular atrophy during their steroid cycles.

The time period which HCG can survive in the human body after being injected is around 3 days. So it should be administered every alternate day for as long as the testes do not start producing testosterone on their own.

After the body is prepared this way, the SERM therapy can be started. If the cycle contained the human growth hormone (HGH), then it needs to be continued in the same manner in the post cycle therapy. This hormone also makes the body retain the gains that were achieved during the cycle.

Coming back to the SERM therapy, it is done to stop the estrogen from inhibiting the pituitary and the hypothalamus from the production of testosterone. The Clomid is actually a medicine that is supposed to boost ovulation in women. But this drug attaches itself to the estrogen receptors inside the pituitary and the hypothalamus. These two glands sense the estrogen level in the blood through these receptors, and according to that, they either start or stop the production of testosterone to maintain homeostasis. When the Clomid molecules attach themselves to these receptors, the glands cannot sense the estrogen.

Nolvadex is another SERM that blocks estrogen, and also works as good as Clomid. In fact, as per some studies, Nolvadex acts best when coupled with HCG. This is for the fact that if HCG doses are too high, Nolvadex blocks the estrogen arising from aromatization, and does not let the leydig cells to become desensitized. This helps in the better release of testosterone. Some people are also of the opinion that it is best to use Nolvadex along with Clomid because that gives the ultimate synergistic effect.

Anyway, the levels of testosterone are low in the body as it is. The glands are blocked from sensing the high levels of estrogen now due to the SERM. This is seen as low testosterone levels in the blood. The pituitary and hypothalamus then signal start of the production of testosterone to the testes. Clomid and Nolvadex are both available in tablet and liquid form. Nolvadex is also used to treat cancerous tissue which is sensitive to estrogen, like breast cancer. Using too much of HCG for a long period of time may cause the leydig cells in the testes to get desensitized. This will not be good for the body. Also, HCG greatly aromatizes into estrogen, so taking higher doses of this hormone should always be coupled with anti-estrogen. That will help prevent conditions like gynecomastia.

High levels of HCG may also cause the production of progesterone in the testes. To prevent this, any aromatase inhibitor like Letrozole or Arimidex can be used. But if any such inhibitor is used, then Nolvadex should not be included in the post cycle therapy plan. This is because Nolvadex directly counteracts the actions of these inhibitors, especially Arimidex, and vice versa. If Nolvadex has to be used, then Aromasin should be the aromatase inhibitor of choice, since Aromasin does not react with Nolvadex in any manner.

Apart from not interfering with Nolvadex, Aromasin is also known to be able to help in the production of testosterone, as well as negatively affect cholesterol levels. This makes it an ideal choice for the post cycle therapy. Cycling between anti-estrogens is always good for consistently keeping the levels of estrogen low in the bloodstream.

bodybuildingEveryone knows that there are steroids which are excellent for gaining muscle mass and strength. However, the professional bodybuilders and steroid consumers heard about bulking cycles. A bulking cycle is a period in which you take steroids to gain muscle mass, weight and strength. During this period, you will also get fat, and if you can’t control your fat body, then you will have to take steroids which are designed for the fat burning.

Remember that even if you want to start losing weight by using steroids, you will still have to work out or even to follow a strict diet; otherwise you won’t burn any calorie. The first mistake clenbuterol nakshang. Those who have a bit of knowledge about steroids are making one of the biggest mistakes. They consider that Clenbuterol and Cytomel are weight-loss steroids, when they are HGH, which means Human Growth Hormones. However, these hormones are providing a better fat losing process than the steroids.

As an example, Cytomel is a synthetic T3 hormone which is having the effect of requesting a greater energy for your body to work. It means that you will do a higher effort with everything you do and this way you will start losing fat. Those are just hormones, but there are also steroids which are helping you a lot to get rid of extra kilos. One of the best examples will be Winstrol.

One of the most popular steroids which are designed for fat loss is Winstrol. This steroid is particularly use for cutting a bulking cycle, when the results are not very good. However, even if you take Winstrol or any other hormones for losing fat, you will still have to work out in order to get rid of the kilos.
A lot of people are really considering cutting off their bulking cycle, because the results are unpleasant. Some of them are getting fat, instead of getting muscles, because they followed the right treatment with steroids, but the workout didn’t work as they expected. When a cycle is not offering the desired result, then they will have to start losing weight, using another set of steroids and hormones.

Some doctors might not recommend something like that, because it could be harmful for the body, but when someone wants to gain muscle mass fast, and then he or she will certainly want to lose the fat fast. There are a lot of places in which you can find steroids and hormones.

As an example, Clenbuterol, Cytomel and Winstrol are very popular for losing weight. How healthy are the HGH and steroids Usually people are considering that the steroids and HGHs are very damaging for the human body. Yes, they actually are if you are not taking them according to a strict advice. It’s always a good idea to visit a doctor, a gym trainer or a bodybuilder before starting a bulking cycle or before stopping a cycle.

These products are not that harmful, especially if they are original, because on the black market you can easily get cheated and you can purchase fake steroids made from low-quality substances. The best example to prove that the steroids are not harmful is the fact that they will not produce any muscle or they will not eliminate any fat from your body unless you’re not working out. They are just helping the human body to get in the point that everyone wants but they are not replacing the training or the diet. We never get bored to repeat that caution is needed when steroids are used. Here are the what steroids effects on human body. Keep this image in mind every time you think about increasing the  dosage or cycle length.

bodybuildingTesamorelin, (formerly known as TH9507), is a type of peptide called a growth hormone-releasing factor (GHRF). GHRF causes growth hormone to be created and spread in the body, which helps increase metabolism, reduce belly fat, improve body shape, and use of energy. Tesamorelin (formerly known as TH9507) is a synthetic growth hormone-releasing factor that stimulates the pituitary gland in the brain to secrete growth hormone; this indirect approach appears to maintain more stable, natural levels, like CJC-1295. Clinical trials have shown that Tesamorelin significantly reduces abdominal fat with fewer side effects than human growth hormone itself, although abdominal fat may return after the Tesamorlein is discontinued (depending upon the individual). Tesamorelin has been shown to reduce lipodystrophy in HIV-infected individuals as well as similarly reducing abdominal fat in NON-HIV-Infected individuals.

Tesamorelin is a stabilized analogue of the growth hormone-releasing factor (GRF) that induces growth hormone (GH) in a specific and physiological manner. To date, clinical studies suggest that Tesamorelin reduces visceral fat in HIV-infected patients with abdominal lipo-hypertrophy as well as reducing abdominal fat in all individuals studied.

A peptide that increases growth hormone release improved several measures of cognitive function in cognitively normal and mildly impaired older individuals in a placebo-controlled trial, a researcher said here. Scores on standard tests of executive function and verbal memory were significantly higher in participants given Tesamorelin, a synthetic analog of growth hormone releasing hormone (GHRH), in a 20-week trial, according to Laura D. Baker. Participants taking the drug in the 78-person trial also reported greater subjective improvement in cognition relative to the placebo group.

In animal studies, GHRH administration improved bio-markers of brain function as well as performance on cognition tests. And a 2006 clinical trial with GHRH found small but significant improvements in cognitive test scores in healthy older adults. In the current study, funded by the National Institute on Aging, 41 cognitively normal adults and 37 with mild cognitive impairment were randomized to placebo or Tesamorelin at 1 mg/day subcutaneously. Mean participant age was 66 to 70 among the four groups. Scores on the Mini-Mental State Examination averaged 29 for the normal participants and 28 for those with mild impairments. Normal and impaired participants differed more at baseline on a test of story recall, with mean scores of 54 and 44, respectively. Tesamorelin appeared to have a protective effect relative to placebo among the cognitively impaired patients on this measure. Tesamorelin has been shown to reduce lipodystrophy in HIV-infected individuals. Lipodystrophy is a condition that causes changes in placement of body fat, including wasting and fat accumulation, and changes in metabolism. Similar to Tesamorelin is Sermorelin, which may be taken with GHRP-6 is clinical trials, that also promotes HGH production and possible fat loss. Individuals with lipodystrophy may develop excess fat most notably around the liver, stomach and other abdominal organs (visceral body fat).

hormone_balance_andropauseThe Andropause is the time in a man’s life when the hormones naturally start decline usually during their late forties or early fifties. This decline continues into the eighties. Many have questioned whether the male menopause is more myth than reality. The Andropause is a gradual process and not exactly the same as menopause. However, like women undergoing menopause, the decline in hormones in men result in them suffering from symptoms of the Andropause. However, like the menopause, symptoms of Andropause can vary from person to person.

Between the ages of 50 to 70, some men report symptoms such as erectile dysfunction (failure to achieve an erection), general tiredness, mood changes, night sweats and sometimes palpitations. Most men attribute erectile dysfunction to be the most significant event of the Andropause. Apart from erectile dysfunction, mood changes can take place too. Some patients of mine have complained of nervousness, irritability and even depression. Other patients undergoing andropausal changes report the feelings of wanting to be closer to family and friends. Men often focus too intently on their career, money and power in their earlier life, often neglecting family and friends. In the andropausal years, men and take on a more “maternal” role, as if transitioning to become more motherly than fatherly. They become more concerned about their friends and family, as if regretting their former attitudes. It is interesting that many patients do not sense these changes in themselves, but rather it is women that notice this and tells me that he is undergoing “the menopause”.

In andropausal men, night sweats and palpitations occur because of an overactive autonomic system in response to falling testosterone levels. To assess for hypogonadism, which is in part the clinical basis of the Andropause, the doctor will check for physical signs in men including hair loss particularly in the armpit and genitalia. Psychological tests may be carried out to rule out depression and other mood and cognitive changes. Although once willing to take risks of all sorts, the andropausal man becomes more conservative and fears treading in unclear waters. Productivity is at the core of a man’s being. He feels happy when he creates something and is being noticed for it. He wants to feel contributory to his family and society. All his life he struggles to be the breadwinner for the family, and to get recognition at work for his efforts. In the days of early man, hunting and providing for his family and society was at the hub of function. For modern man, there may not be a need for barbaric hunting, but the board room still makes the same demands on his skills and abilities, and managing those complex business deals is akin to modern hunting. Andropause is a time of decline, when he is no longer as productive as he was before. Often he makes even less money than when he was younger, and feels threatened by younger more aggressive males biting into his turf. A man’s personality may not stay the same over the years of his life. In younger days the fiery younger male is impulsive, intolerant and ambitious. With the passage of time, various experiences and the fall in testosterone, quite a different male may emerge in later years. The red hot male often converts to a mellow yellow version, becoming more “feminine” and “domesticated”, and taking on less challenges in the outside world, often preferring the cozy security of family and close friends. He is much less active, prefers his couch to watch television, and becomes weaker from lack of exercise. Deep inside every man is the desire to remain young and be that little boy that he once was. This may become more marked after retirement as usually there is more spare time at hand. The andropausal man may relive his childhood days, often to the amazement of his partner or spouse. The mischief may be an extramarital affair, a new red sports car, a sudden passion for toy train sets, riding a bicycle, which he hadn’t done for years and so on. Many doctors think, that many hormones have been approved for human use and yield positive results. Melanotan is a peptide that is produced in the body as a way of making an animal’s skin tan. This is used as a response to exposure to UV rays to protect the animal’s body against skin cancer and other damage. This chemical has been synthesized as melanotan 2, which was developed by researchers at the University of Arizona. This synthetic analog mimics the behaviors of the melanocortin peptide hormone alpha-melaocyte stimulating hormone. The synthetic version of this peptide has been found to produce similar melanogenesis effects and aphrodisiac effects in animal test subjects, in the initial clinical trials that have been performed. To date, no compounds that contain melanotan 2 peptides have been approved for human use as clinical trials are still ongoing. However, initial research indicates that this peptide may be very useful in preventing a variety of cancers and other diseases if the effects of it can be regulated to minimize side effects.

Sustanon_250Sustanon 250 is a testosterone mixture first developed by Organon in an effort to create a more suitable testosterone for hormone replacement therapy. The idea was simple; create a testosterone that can be injected less frequently and still keep levels at a steady rate over a long period of time. The good news for HRT patients is the idea became a reality, the bad news for the performance enhancer is this does not help them at all. Were not saying Sustanon-250 is useless to athletes, far from it but the time release principles are of very little value to them because they will necessarily need more testosterone than an HRT patient and will need to keep levels at a maximum range; well explain as we go along.

The Sustanon 250 Mixture:
Most testosterones are defined by their name; for example, Testosterone-Enanthate is called so because it is a testosterone with the Enanthate ester attached, pretty simple. However, there is no Sustanon ester, Sustanon 250 refers to a blend of 4 varying ester based testosterones each with a varying half-life mixed together in varying doses.

The total mixture, which gives us 250mg per milliliter is as follows:

Testosterone-Propionate 30mg
Testosterone-Phenylpropionate 60mg
Testosterone-Isocaproate  60mg
Testosterone-Decanoate 100mg
With this mixture we have two relatively fast esters in Propionate and Phenylpropionate, a moderate size ester in Isocaproate and a very long ester in Decanoate. Once injected testosterone will be released at a fairly even rate regarding milligrams for a month, making this a near perfect HRT medication but for performance purposes this will not do. Because of the short esters attached, to maintain peak testosterone levels Sustanon 250 must at a minimum be injected every three days with every other day administration being far more optimal because of the Propionate ester attached.

Sustanon 250 and Omnadren:
Many steroid users who supplement with Sustanon 250 find Omnadren to be equally effective, in-fact, almost everything that can be said of Sustanon 250 can equally be said of Omnadren; these two testosterone mixtures are almost identical in action. The only significant difference is one ester, while the longest ester in Sustanon-250 is Decanoate the longest ester in Omnadren is Caproate. The dosing of each ester in each blend is exactly the same, Omnadrens final Caproate ester is dosed at 100mg just as the Decanoate ester is in Sustanon 250. However, because Caproate carries with it a shorter half-life than Decanoate Omnadrens total half-life is going to be approximately ten days while Sust as its commonly called will carry a total half-life of approximately 15 days.

Benefits of Sustanon 250:
The benefits of Sustanon 250 are the same as any testosterone be it a single ester or testosterone blend such as Omnadren or Testoviron. All testosterone users of all forms can greatly increase lean muscle tissue as well as increase strength and vitality. Further, as testosterone is a key component in maintaining muscle mass in a calorie restricted diet it is the perfect hormone when we are trying to lean out. Further, because testosterone blocks and reduces muscle wasting hormones that buildup in the body, overall, regardless of the purpose of use we inevitably create a more pleasing physique when testosterone levels increase.

There is however a risk to reward ratio that is in play and it applies to all testosterone, Sustanon 250 makes no exception. The principle is simple; the more you use the greater the benefits will be but the more you use the greater the risk of nasty side-effects. Sustanon 250 carries the exact same side-effects of all testosterone compounds, the same as Testosterone Enanthate, Testosterone Cypionate or any other single ester or mixture you may desire to use. All testosterone use opens the door for an aromatizing effect so estrogenic related side-effects will always be a concern. Issues such as Gynecomastia, high blood pressure, water retention and other estrogenic effects such as decreased sex drive can occur. This is why it is of utmost importance to use a good aromatase inhibitor when supplementing with testosterone, by doing so, coupled with using responsibly we greatly improve our chances of positive and enjoyable use.

bodybuildingGynecomastia (male breast enlargement) is a condition no man desires; not only is it unpleasant at best even the idea of it is horrifying. While Gynecomastia is by no means life-threatening it can be severely damaging to one’s personal state of mind, as it can cause the best looking physique in the world to look like a giant heap of garbage. There are many forms in-which Gynecomastia can take and many starting points that led to the condition. However, some are simply due to age and hormonal imbalances and many cases are due to anabolic steroid use, again, causing a hormonal imbalance.

Gynecomastia is simply a condition in-which the chest of a man begins to take female shape; as is evident by the name itself as Gynecomastia means woman breast. In most cases a hormonal imbalance causes the problem and estrogen buildup is almost always the culprit but progesterone can also play a key role.

There is often a Gynecomastia form known as Pseudogynecomastia that affects many men but this is somewhat of a misguided term. Pseudogynecomastia really has nothing to do with a hormonal imbalance but is rather simply excess adipose tissue in the pectoral region. While simply losing weight will often fix the problem it is nevertheless as bothersome as a pure glandular form.

As it pertains to glandular Gynecomastia there are three common groups of people and surprisingly to many a large portion is comprised of young adolescent boys. Often this is caused by excess hormones being passed on from the mother at birth but fortunately for the majority of young men as they reach adult hood it will normally dissipate; however, approximately 30% of all pubescent Gynecomastia cases will require surgery to remedy. Those who are of an elderly nature may find a similar situation as the young adolescent; as age creeps on hormonal imbalances can occur and because the skin is often softer at an older age it can look pretty nasty. In most cases those who are elderly will only find surgical remedy to be their saving grace; however, hormone replacement therapy does provide a chance of remedy but it is by no means a guarantee.

Anabolic steroid users are some of the highest risk candidates for Gynecomastia due to the very nature of steroid use and many anabolic steroids direct mode of action once administered to the body. As you understand, most anabolic steroids are testosterone derived and as such they convert to estrogen in the body via the aromatase process via the aromatase enzyme. This process causes a buildup of estrogen in the body that binds to the receptors in the pectorals causing gynecomastia.

Many athletes who use anabolic steroids stave off the effects of Gynecomastia and quite frankly there are really very few people who should ever fall prey if they are responsible and take precaution; however, some will be so sensitive to steroid use that all the precaution in the world will do them no good at all. By-in-large Selective Estrogen Receptor Modulators (SERMs) are the most common means of prevention; including aromatase inhibitors and estrogen receptor antagonists.For decades many athletes who use anabolic steroids have supplemented with the SERM Tamoxifen (Nolvadex) to combat such issues. Nolva, as it is commonly known acts to block the estrogen from binding to the receptors; it does not reduce estrogen as is commonly thought by many who take it. However, while this is a solid prevention measure, for many it is not enough and only an aromatase inhibitor will do. An aromatase inhibitor will actually reduce the amount of estrogen in the body and bind it what’s left. While perhaps not completely accurate but to give you an idea, for the prevention of gynecomastia when steroids are present look at Nolva like Aspirin and aromatase inhibitors like morphine; far stronger. The two most common aromatase inhibitors that will in most cases get the job done include Anastrozole (Arimidex) and Femara (Letrozole.)

???????????????Testosterone Cypionate is one of the most favourite and commonly used testosterones by athletes and performance enhancers such as the daily gym rat looking for a better build. As are all testosterones, Testosterone Cypionate is defined by the ester that is attached, as the testosterone hormone is the same regardless of the ester attached. Perhaps the biggest reason this particular configuration is so favourite is because it is so simple to use, meaning it’s one of the more convenient forms in-terms of application regarding frequency as well as efficiency.

For years an ongoing debate has raged on regarding Testosterone Cypionate and Testosterone-Enanthate revolving around which one is more powerful and the answer is plain. They are equal 100mg of Testosterone Cypionate will yield the same results as 100mg of Testosterone-Enanthate, the two compounds are virtually duplicate. As both types of testosterone are defined by their ester, in this case the Cypionate and Enanthate ester are as closely related as two esters can be. Both forms carry with them a moderately extensive half-life as both are moderately great esters. The difference in half-life is approximately 24hrs and when we’re talking about half-lives that extend well beyond a week the difference is beyond negligible. Testosterone Cypionate possesses a half-life of approximately 12 days while Testosterone-Enanthate carries a half like of approximately 11 days. Even so, some will still hold to Testosterone Cypionate being more powerful but more times than not this is really a cognitive disillusion as there is really no difference between the two compounds.

As a moderately large ester Testosterone Cypionate will need to be injected at a minimum of once per week, a once per week injection will ensure your blood levels remain above baseline. However, once administered blood levels will begin to fall quickly after approximately five days, for this argument most Testosterone Cypionate users will be best served with applying two injections per week in order to maintain steady blood levels at their peak.

The most obvious point of interest revolves around the benefits of Testosterone Cypionate use and the benefits are truly large. Increases in muscle mass and strength can all be readily achieved far beyond what you can obtain without. As a both greatly anabolic and androgenic compound Testosterone Cypionategreatly increases nitrogen in the muscle tissue thereby allowing more protein to be stored, further, Testosterone Cypionate will greatly defend the body from muscle destroying hormones known as corticosteroid hormones which are extremely catabolic. If that’s not enough the benefits go even deeper, because the testosterone hormone increases IGF-1 in the corpse we thereby increase the totality anabolic action within the body when testosterone levels are increased and then it again continues to get even better. Because testosterone binds so efficiently to the androgen receptors which aids in muscle gain it further aids in fat loss as well as repair of muscles once damaged from the stress of training.

For the anabolic steroid user there is nothing more common than testosterone injections for it is the testosterone hormone that will be used most frequently and in injectable configuration. The same can be said of the Hormone Replacement Therapy (HRT) patient, as testosterone injections are often the common form of therapy they will receive. In any case there are things to know and understand so that we may maximize our testosterone use in the most effective and effective means possible but as this is a very well-tolerated hormone and generally very side-effect friendly it is really all very simple. Truth be told, when it comes to testosterone injections there’s really nothing magical happening, there isn’t some monster waiting in the syringe as you may have been led to believe in the past; there’s really a hormone that your corpse has produced all of its existence and one that you are now ready to take advantage of.

Follow

Get every new post delivered to your Inbox.